Education: MD, University G d’Annunzio (Ud’A) Chieti

Residency in Underwater and Hyperbaric Medicine and in Nutritional Sciences, Ud’A Chieti

PhD in Muscle pathophysiology, Ud’A Chieti

Appointments post-MD degree:

2000/2002- Research Scientist, Dept. Anesthesiology and Physiology, SUNY, Syracuse NY

2003-present, Visiting professor for Hyperbaric Medicine, University of Greifswald, Germania

2003/2005- Medical Chief CEMSI, Istituto salernitano di medicina iperbarica

2006/2009- Senior researcher at Physiology Unit, Ud’A Chieti

2008-present, membership Directive Committee Italian Society of Diving and Hyperbaric Medicine.

2009-present, Visiting professor and consultant for Diving and Hyperbaric Medicine, USF, Tampa FL and SUNY, Syracuse NY.

2009/2010, Physician Hyperbaric Unit, Istituto Clinico Città di Brescia.

2009/2010, Consultant for wound care and clinical nutrition, Policlinico di Abano Terme, PD.

2011-present, Consultant for HBO, ATIP Hyperbaric Medical Center Padova.

2011- Assistant Professor (MEDF-01), Physiological Lab, University of Padova.

The mission is to identify the molecular and cellular mechanisms involved in the body’s response to artificial atmospheres due to the effects of pressure per se, gas partial pressure alone, and/or the production of secondary reaction productions such as O2-induced free radicals. Altered pressure environments are routinely encountered in hyperbaric medicine (hyperbaric oxygen therapy), underwater diving (hyperbaric gases) and space exploration (hypobaric gases). The Lab with the recruitments included students and junior faculty with research interests in molecular genetics, biochemical toxicology, pharmacology and sport sciences will maintain training excellence in systems physiology. These studies aimed to investigate the pathophysiology of oxygen toxicity, diving related stresses, and mechanisms of hypoxic response in cells, in animals and humans.

Research areas of interest are the control of breathing, metabolic disorders and enviromental stress on exercise-induced oxygen toxicity.

Clinical areas of interest is the safety of human performance in extreme environments and peri-operative quality of care of the vascular and infective surgical patients; in particular to explore the hypoxia modulation and the mechanisms of action of hyperbaric oxygen therapy.

Primary areas of education include exercise physiology and environmental medicine for Motor Sciences and Medicine Courses, supporting students as GAV coordinator and problem-based learning discussions. Recently Dr. Bosco brought in Padua University a Master Course for Physicians and a Course for technicians and nurses in Hyperbaric Medicine (http://www.unipd.it/medicina-iperbarica; http://www.unipd.it/node/5613).

Five selected publications

  1. EM Camporesi & G Bosco (2003) Ventilation, Gas Exchange and Exercise Under Pressure. In The Physiology and Medicine of Diving, 5th edn. Ed. P. B. Bennett and D. H. Elliott. London: W. B. Saunders Company Ltd: Best Publishing.
  2. Bosco G, Ionadi A, Data PG, Mortola JP (2004) Voluntary breath-holding in the morning and in the evening. Clin Sci (Lond). Apr;106(4):347-52.
  3. Bosco G, Zj Yang, J Nandi, Jp Wang, C Chen, EM Camporesi (2007) Effects of hyperbaric oxygen on glucose, lactate, glycerol and antioxidant enzymes in the skeletal muscle of rats during ischemia and reperfusion. Clin Exp Pharmacol Physiol 34, 70-76.
  4. Bosco G, Yang Zj, Di Tano G, Camporesi EM, Faralli F, Savini F, Landolfi A, Doria C, Fanò G. (2010) Effect of in-water versus normobaric oxygen pre-breathing on decompression-induced bubble formation and platelet activation. J Appl Physiol. May;108(5):1077-83.
  5. Bosco G, Casarotto A, et al. Preconditioning with Hyperbaric Oxygen in Pancreaticoduodenectomy: a Randomized Double-blind Pilot Study. Anticancer Res. 2014 Jun;34(6):2899-906.